e. coli bacteria

Smartphone Camera Test for Urinary Tract Infections

Researchers at the University of Bath have developed a simple point-of-care test for urinary tract infections that uses a smartphone camera. The system can rapidly detect the presence of E. coli in urine samples and could guide doctors in their decision to prescribe antibiotics, ensuring appropriate patient care and avoiding the overuse of antimicrobial medication.  It can sometimes be difficult for clinicians to know whether to prescribe antibiotics. Unnecessary use of antibiotics is resulting in antimicrobial resistance, which will pose significant challenges to healthcare in the coming years. However, if a patient has an infection, such as a urinary tract infection (UTI), then antibiotics are undoubtedly warranted, but it can sometimes be difficult for a clinician to know for sure if a patient’s symptoms are caused by an infection. Read more.

Source: Medgadget, January 9, 2020

product approval introduction

FDA Approves New Drug for UTI, Two Devices for OAB/Incontinence

November 2019 proved to be a fruitful month for urology-specific FDA approvals, with the agency giving the green light to a new drug for complicated urinary tract infection, an implantable device for the treatment of overactive bladder/retention, and a digital product for strengthening of pelvic floor muscles and treatment of urinary incontinence in women.  The FDA approved cefiderocol (FETROJA) in patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis, caused by the following: susceptible Gram-negative microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Enterobacter cloacae complex. Read more.

Source: Urology Times, December 4, 2019

e. coli bacteria

Urinary Tract Infections Affect Millions. The Cures Are Faltering

For generations, urinary tract infections, one of the world’s most common ailments, have been easily and quickly cured with a simple course of antibiotics. But there is growing evidence that the infections, which afflict millions of Americans a year, mostly women, are increasingly resistant to these medicines, turning a once-routine diagnosis into one that is leading to more hospitalizations, graver illnesses and prolonged discomfort from the excruciating burning sensation that the infection brings. The New York City Department of Health has become so concerned about drug-resistant U.T.I.s, as they are widely known, that it introduced a new mobile phone app this month that gives doctors and nurses access to a list of strains of urinary tract infections and which drugs they are resistant to. Read more.

Source: New York Times, July 13, 2019

medical research

Smart Diaper Detects Urinary Tract Infections

Urinary tract infections (UTIs) are dangerous for infants and the elderly. While the onset of UTIs generally involves pain and other symptoms, young children are not able to describe how they’re feeling, while the elderly may suffer from neurodegenerative conditions that reduce sensation in the affected area. Moreover, it’s difficult to obtain a sample for testing from those that wear diapers. Now, engineers at Purdue University have developed a sensor-embedded diaper that can accurately point to the presence of a bacterial infection in the urinary tract. Read more.

Source: Medgadget, June 25, 2019

Bacteria

Why So Many Older Women Develop UTIs

Urinary tract infections are one of the indignities many women face as they age. One reason why is because their bladder walls can be invaded by several species of bacteria, a new study finds.  Urinary tract infections, or UTIs, are among the most common type of bacterial infections in women, accounting for nearly 25% of all infections. UTI recurrence rates can range from 16%-36% in younger women to 55% in postmenopausal women.  In the new study, researchers at University of Texas Southwestern (UTSW) in Dallas analyzed bacteria in bladder biopsies from 14 postmenopausal women with recurrent UTI. The investigators found that, in these patients, several species of bacteria can get inside the bladder’s surface area. Read more.

Source: HealthDay News, May 20, 2019