operating room surgery

Tepha Initiates Clinical Evaluation of P4HB Regenerative Scaffold for Stress Urinary Incontinence

Tepha has announced the initiation of a pilot clinical evaluation of the Company’s P4HB regenerative polymer scaffold for the surgical treatment of stress urinary incontinence (SUI).  The study was initiated in Cape Town, South Africa in partnership with the Pelvic Floor Foundation of South Africa(“PFFSA”) and the University of Cape Town.  The first procedures were performed by co-principal investigators, Dr. Stephen Jeffery of the University of Cape Town and Professor Jan-Paul Roovers of the Academic Medical Center, Amsterdam, The Netherlands.  The Cape Town SUI study represents the first clinical application of Tepha’s P4HB polymer technology in the field of urogynecology.  Based in Lexington, MA, Tepha is the pioneer developer and exclusive supplier of the P4HB polymer for medical applications that include hernia repair, plastic surgery, tendon & ligament repair, and wound closure. Read more.

Source: Compelo, February 28, 2019

operating room surgery

London Researchers Examine Psychological Fallout of Incontinence Surgery Complications

London researchers are zeroing in on the potential psychological effects of complications from women’s incontinence surgery, uncovering an increased risk of depression and self-harm after the corrective surgery.  Researchers at the Western University branch of Toronto-based Institute for Clinical Evaluative Sciences and Lawson Health Research Institute — the research arm of the London Health Sciences Centre and St. Joseph’s Health Care London — examined patient outcomes after pelvic mesh implants from January 2004 to December 2012. Using 12 years of data from Ontario’s public health-care system, researchers studied the files of 57,611 women who underwent the midurethral mesh sling procedure during the study period. Of those, 1,586 went under the knife again to correct a complication from the mesh. Read more.

Source: The London Free Press, January 9, 2019

surgeons perform pelvic organ prolapse surgery

Australia Bans Use of Vaginal Mesh Implants for Prolapse

An Australian watchdog has banned the use of controversial vaginal mesh implants for prolapse after a review found “the benefits do not outweigh the risks these products pose to patients”.  The Therapeutic Goods Administration has decided to remove the use of mesh products in the treatment of pelvic organ prolapse and single incision mini-slings which is used to treat urinary incontinence. This move follows the news that NICE, the health watchdog in the UK, will recommend that mesh should be banned as a routine treatment for prolapse, a condition when organs such as the vagina, uterus or bowel fall down or slip out of place. The draft guidance, seen by Sky News and due to be published next month, states that mesh implants for prolapse should now only be used for research purposes. It does not affect the use of mesh for incontinence which accounts for the majority of operations. Read more.

Source: Sky News, November 29, 2017

operating room surgery

Majority of Incontinence Treatments Deliver Poor Results

Surgery is the most reliable method of treatment for incontinence – curing the condition in just over eight in ten cases; other types of treatment, meanwhile, do not deliver the same kind of success. These are the findings of a comprehensive systematic overview of cure rates for the treatment of incontinence around the world during the last ten years. “Unfortunately we are not actually curing the condition in that many cases. Surgery aside, the results delivered are poor. And the problems are only going to get worse in the future because the population, as we know, is aging,” says Ian Milsom, Professor of Gynecology and Obstetrics at the Sahlgrenska Academy and Head of the Gothenburg Continence Research Center (GCRC). Read more.

Source: Science Daily, April 4, 2017

Artificial Sphincter Surgery for Bowel Incontinence

external sphincter muscle squeezing

This shows the external sphincter muscle properly squeezing and keeping fecal matter inside until he proper time.

Everyone has a pelvic floor: it is a hammock of muscles that lies in your pelvis, supporting your internal organs in that area (bowel, bladder, and – in women – the uterus) and keeping them in the correct place. In your pelvic floor are a few muscles that are called “sphincters”.  There is an internal and external sphincter surrounding the anus. These anal sphincter muscles naturally contract around the rectum and keep the fecal matter inside your body until you relax the sphincters at a socially-acceptable time (generally when you’re using a toilet).  As the urge to defecate increases, you can contract (or squeeze) your sphincters to gain more control.  When you cannot control these sphincter muscles, bowel incontinence (also called accidental bowel leakage or fecal incontinence) may happen.

Surgery to implant an artificial sphincter involves placing an inflatable sphincter around the anus. A pump (placed inside the body in the labia or scrotum) is used to deflate the device, allowing fecal matter to pass through at the appropriate time. The device automatically refills after ten minutes, once again closing off the rectum.Continue reading