spine anatomy

Astellas Wins Expanded Label to Include Pediatric Use for Oral Solifenacin in the EU

Tokyo-based Astellas Pharma (TYO: 4503) has been awarded EU approval for its neurogenic detrusor overactivity (NDO) therapy solifenacin succinate in oral suspension form. The drug is indicated for children aged 2 to 18 years.  NDO is a bladder dysfunction in which increased storage pressure can put the upper urinary tract at risk of deterioration.  Commonly observed in patients with conditions such as multiple sclerosis and spinal cord injury, it causes urinary incontinence in approximately 50% of MS patients. Read more.

Source: The Pharma Letter, March 9, 2018

CompactCath

CompactCath, a Discreet, Compact, Hygienic Urinary Catheter Cleared in EU

The San Francisco Bay Area may be best known for information technology startups, but there are other small companies around that develop very different technologies. CompactCath has created a urinary catheter that solves some of the persistent issues that users of such devices have to face every day, and the company just announced that its eponymous device received CE Mark approval in Europe. About a year ago the CompactCath received FDA clearance. Read more.

Source: Medgadget, December 13, 2017

A Neurogenic Bladder Due to Marfan Syndrome

My Story – Submitted by: Carl

I first noticed urinary leakage in January, 1985, and simply changed my pjs and underwear. However, within weeks, I found myself changing my underwear several times each day, and staining my bed sheets. After my first accident, I panicked, went to my PCP, and was referred to the first of a series of urologists, none of whom took my situation seriously. The urinary pain began almost simultaneously with the onset of the incontinence, though the spasms were infrequent and not really painful; they were just bad enough to get my attention. I joined the Simon Foundation and through it discovered folks, whom I later discovered to be AB/DL, who patiently taught me much of what I would need to know to get through life as an incontinent. Though I am not one of their number, I owe them much.Continue reading

Neurogenic Bladder

Drawing of a brain, spinal cord, and bladder

Damage to nerves may cause a neurogenic bladder.

Injuries, surgeries, diseases and birth defects may affect the how the body’s nerves work … or don’t work! Some medical conditions that commonly affect how our nerves work include Spina bifida, Multiple sclerosis (MS), Type 1 and 2 Diabetes, spinal cord injuries (SCIs), Parkinson’s disease, and stroke. And each of these conditions may create a neurogenic bladder.  A neurogenic bladder is a disorder of the lower urinary tract that is the result of damage to — or diseases of — the nervous system leading to a loss of voluntary control of your bladder.  Continue reading