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Latest Research, Industry, Medical and Scientific News

hurrying with overactive bladder

Innovus Pharma Announces the Publication of a Successful Clinical Trial in Overactive Bladder and Urine Incontinence Patients for its UriVarx® Product

Innovus Pharmaceuticals, Inc. (“Innovus Pharma” or the “Company”) (OTCQB Venture Market: INNV), an emerging commercial-stage pharmaceutical company that delivers safe, innovative and effective over-the-counter medicine and consumer care products to improve men’s and women’s health and respiratory diseases, today announced that the human clinical trial for the patented formulation in its product UriVarx® product for bladder health was published in the peer reviewed journal, BMC Complementary and Alternative Medicine (Schoendorfer et al. BMC Complementary and Alternative Medicine (2018) 18:42). The study was conducted by the team of Dr. Niikee Schoendorfer in Australia in collaboration with the Company’s UriVarx® licensing partner Seipel Group, Ltd. The outcome of this study demonstrated both statistical significance and clinical relevance in reducing symptoms of Overactive Bladder (“OAB”), urinary frequency and/or urgency and incontinence. Read more.

Source: Digital Journal, February 7, 2018

surgeons perform pelvic organ prolapse surgery

New Zealand’s Medsafe regulatory body removes pelvic mesh products from market

New Zealand’s regulatory body Medsafe has taken steps to remove a number of surgical mesh products from the country, according to a release posted today. The agency said the product’s removal was the outcome of a recent regulatory action on surgical mesh products, specifically those designed for treating pelvic organ prolapse via transvaginal implantation and one mini-sling product designed to treat stress urinary incontinence. Medsafe said that last December it requested safety information from four surgical mesh suppliers in New Zealand, following action taken by Australia’s TGA as it looked to review meshes used for urogynaecological use. The earlier TGA’s investigation ended in regulatory actions to remove the devices from the market, MedSafe said, and similarly resulted in their removal from New Zealand’s market. Read more.

Source: +Mass Device, January 31, 2018

pregnancy woman childbirth

There Are Some Benefits to C-Sections, Researchers Say

It may seem like undergoing surgery to have a child wouldn’t have a lot of advantages, but it turns out there may be some benefits to having a cesarean section.  Experts warn, however, that it doesn’t mean you should schedule the operation unless it’s needed.  A study in PLOS Medicine concluded that women who have cesarean deliveries (also known as C-sections) have a lower risk of urinary incontinence and pelvic prolapse.  Dr. Sarah Stock, who researches preterm birth at the University of Edinburgh in Scotland, and her team looked at one randomized controlled trial and 79 cohort studies involving nearly 30 million women.  The studies looked at long-term outcomes of women who had the surgery compared to those who delivered vaginally. Read more.

Source: Healthline, January 23, 2018

drugs for overactive bladder (OAB)

Urinary Incontinence: What Pharmacists Should Know

Urinary incontinence (UI), the involuntary leakage of urine, is a frequent and problematic chronic condition for many patients. An estimated 10 to 30% of men and women are affected nationally, though this may be underestimated due to underdiagnoses and undertreatment.1-3 Often, patients who suffer with UI symptoms will develop poor self-rated health, depression, and mobility disability.4,5 This comorbid disease state also presents a substantial financial burden; data from 2014 found that in the United States alone, an estimated $65.9 billion in direct and indirect costs were spent for UI treatment.3  Read more.

Source: Drug Topics, January 23, 2018

medical research

Magnets and MicroRNAs: A Therapeutic Duo That Could Help Relieve Constipation

It is fairly common to think of constipation in a humorous light. However, anyone who has suffered from the debilitating condition can attest that it is far from a laughing matter.  With a sizable percentage of the population increasing in age and opioid abuse reaching epidemic proportions, investigators are looking for new tools to help patients ease their gastrointestinal suffering. Now, investigators from Thomas Jefferson University (TJU) have just released data of a new technique—called magnetofection—that incorporates micro-metal beads coated with small RNA fragments (microRNAs, or miRNAs) injected at specific regions of the colon and held in place with a powerful magnet. Read more.

Source: Genetic Engineering and Biotechnology News, January 17, 2018

sleep woman

Sleep Quality Improves with Help of Incontinence Drug

A drug used to curtail episodes of urinary incontinence in women also improves quality of sleep, a researcher at the Stanford University School of Medicine reports.  People who experience urinary incontinence, especially at night, often have trouble maintaining normal sleep cycles. Now, the Stanford researcher sees promise in using one drug to help remedy both problems.  “Two of the biggest quality-of-life factors for older women are poor sleep quality and incontinence, and the older you get, the more prevalent both conditions are, and they do seem to be correlated,” said Leslee Subak, MD, professor and chair of obstetrics and gynecology. “And so, if we can find a drug to treat one and effectively decrease the other too, that could be big for improving quality of life.”  Read more.

Source: Stanford Medicine News Center, January 11, 2018

You may also with to read:  Incontinence Drug May Help Sleep Dysfunction in Older Women