stem cells

Engineering Digestive System Tissues: Significant Progress

Researchers at Wake Forest Institute for Regenerative Medicine have reached important milestones in their quest to engineer replacement tissue in the lab to treat digestive system conditions — from infants born with too-short bowels to adults with inflammatory bowel disease, colon cancer, or fecal incontinence.  Reporting today in Stem Cells Translational Medicine, the research team verified the effectiveness of lab-grown anal sphincters to treat a large animal model for fecal incontinence, an important step before advancing to studies in humans. And last month in Tissue Engineering, the team reported success implanting human-engineered intestines in rodents. Read more.

Source: Science Daily, July 5, 2017

business buildings

RDD Pharma Receives Orphan Designation for RDD-0315 in Spinal Cord Injury Patients

RDD Pharma, a leader in developing treatments for anorectal disorders, announced today the European Medicines Agency’s Committee for Orphan Medicinal Products has granted orphan designation for RDD-0315, an investigational drug for the treatment of fecal incontinence in patients with spinal cord injury.   The committee recognized that RDD-0315 may be of significant benefit to spinal cord injury patients affected by fecal incontinence. “We are pleased the EMA recognized the clinically significant benefit that RDD-0315 may offer spinal cord injury patients,” stated Jason Laufer, Chief Executive Officer, RDD Pharma.  ‘We have the potential to positively impact the health, well-being and quality of life in this patient population. ‘  Read more.

Source: PRNewswire, July 5, 2017

 

Christine Norton, PhD

2017 John J. Humpal Award Presented to Professor Christine Norton at Innovating for Continence Conference

The John J. Humpal award was presented to Professor Christine Norton at the Simon Foundation for Continence’s sixth biennial Innovating for Continence: The Engineering Challenge conference, hosted April 19-21 at the Millennium Knickerbocker Hotel, in Chicago, IL, USA.

Christopher Payne, MD, Emeritus Professor of Urology at Stanford University presented the John J. Humpal award to Christine Norton, PhD, MA, RN. Dr. Payne asked the conference attendees, “What makes a young, talented nurse scientist choose the field of fecal incontinence? While I don’t have the exact answer to that question, we are certainly lucky that she did. I first met Christine at the WHO International Consultation on Incontinence in 2005 and was struck by the clarity and insightfulness of her committee’s findings. Christine achieved the classic goal for medical faculty with major contributions in teaching, education, and clinical care. In fact, there is practically nothing in the entire field to which she has not contributed. For this she was awarded an endowed professorship. I’m a bit jealous, but very proud to be her colleague, and to present her this well-deserved award.”

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clostridium difficile

ConvaTec Releases New Fecal Management System in US

Global medical technology company ConvaTecGroup announced the US launch of the Flexi-Seal PROTECT Fecal Management System on Tuesday, following receipt of 510(k) clearance from the US Food and Drug Administration.  The FTSE 100 firm said Flexi-Seal PROTECT FMS was the latest addition to the company’s “market-leading range” of advanced systems developed to manage acute fecal incontinence, and help to reduce the associated risks of skin breakdown and spread of C. difficile infection.  Read more.

Source: digitallook.com, May 2, 2017

surgeons perform pelvic organ prolapse surgery

How a Ring of Titanium Beads Can Help Fecal Incontinence

A new device made up of magnetic titanium beads may help certain patients who have problems controlling their bowels, a condition called fecal incontinence.  The Fenix® Continence Restoration System mimics the function of the anal sphincter. It is the newest treatment option available to certain patients who have fecal incontinence caused by childbirth complications, trauma, prior surgeries, anal sex or another cause of muscle and nerve damage.  Read more.

Source: Cleveland Clinic, March 9, 2017

Health Canada logo

Axonics Sacral Neuromodulation System Receives Marketing Approval

Axonics Modulation Technologies, Inc. announced today that it received a Homologation d’un instrument médical (medical device approval) for the first rechargeable Sacral Neuromodulation (r-SNM™) System® to treat Overactive Bladder (OAB), Fecal Incontinence and Urinary Retention.  The Health Canada license confirms that the Axonics® product meets all of the Canadian Medical Devices Regulations, Section 36, for Active Implantable Medical Devices and enables Axonics to market its r-SNM System throughout Canada. Read more.

Source: Yahoo! Finance, January 5, 2017

Learning to Live with Bladder and Bowel Incontinence

My Story – Submitted by: Shawn

Hello all! My name is Shawn and I am 39 years old and I am bowel and bladder incontinent. This started for me about 2 years ago. Well, l started out driving dump trucks for months and theses guys were dropping 2-3 thousand pound rocks into my truck. Jarred the snot out of me and knocked the wind right out of me several times. I started having issues with balance, feeling lightheaded all the time, blood pressure issues, couldn’t think or reason. And then one day I was sitting in bed talking to my wife, and wammo! I was wet. Soaked! Started having issues during the day peeing my pants and started wetting at night.Continue reading

Gallbladder, Kidney Stones, and Incontinence

My Story – Submitted by: Anonymous

I’ve always had some bedwetting problems, but in the last few years they have become worse due to the fact that I have passed several kidney stones over the years, and it has affected my kidneys, and caused me to wet the bed more than usual. I have tried several different things, and none of them seem to have any affect on the bedwetting problem. Continue reading

A Christmas Gift

My Story – Submitted by: Nancy

It was April 2012 and I was 48 years old. I had been struggling with back problems-herniated disc on the shoulder and middle of the back and a continuing gnawing in my pelvic area. After many MRI and CT scans the doctors recommended physical therapy and an occasional pain med. As I actively participate in my doctor’s program I did have relief in my back. However the gnawing feeling in my pelvic was not correcting itself. Then one day while waiting for my physical therapist in the waiting room I had my first incident of bowel incontinence. I was mortified! I saw my pain management doctor that day. The next few days were filled with nerve tests and CT Scans. Nothing showed up on the tests. Though I kept having bouts of bowel incontinence. I was also losing weight and very fatigued. Finally I began searching the web for help and found Simon Foundation for Continence. This was my life saver. I read many articles on the site and one of them suggested seeing a gastroenterologist for medications and to be given a diet.Continue reading

Bowel Incontinence or Accidental Bowel Leakage (ABL)

bowel incontinence occurs in the digestive system

Bowel incontinence or ABL occurs when stool or gas unexpectedly leaks from your rectum.

Bowel incontinence, which may also be referred to as fecal incontinence, anal incontinence or Accidental Bowel Leakage (ABL), is when stool or gas unexpectedly leaks from your rectum. Sometimes you feel the urge to have a bowel movement, but can’t reach a bathroom in time.

The U.S. National Institutes of Health’s Bowel Control Awareness Campaign reports that more than 18 million Americans have bowel incontinence. As with urinary incontinence, bowel incontinence affects people of all ages, races, and both sexes. However, it is more common in women than in men, and it affects the elderly more often than younger adults (although it is not a normal part of aging).Continue reading