stem cells

Engineering Digestive System Tissues: Significant Progress

Researchers at Wake Forest Institute for Regenerative Medicine have reached important milestones in their quest to engineer replacement tissue in the lab to treat digestive system conditions — from infants born with too-short bowels to adults with inflammatory bowel disease, colon cancer, or fecal incontinence.  Reporting today in Stem Cells Translational Medicine, the research team verified the effectiveness of lab-grown anal sphincters to treat a large animal model for fecal incontinence, an important step before advancing to studies in humans. And last month in Tissue Engineering, the team reported success implanting human-engineered intestines in rodents. Read more.

Source: Science Daily, July 5, 2017

business buildings

RDD Pharma Receives Orphan Designation for RDD-0315 in Spinal Cord Injury Patients

RDD Pharma, a leader in developing treatments for anorectal disorders, announced today the European Medicines Agency’s Committee for Orphan Medicinal Products has granted orphan designation for RDD-0315, an investigational drug for the treatment of fecal incontinence in patients with spinal cord injury.   The committee recognized that RDD-0315 may be of significant benefit to spinal cord injury patients affected by fecal incontinence. “We are pleased the EMA recognized the clinically significant benefit that RDD-0315 may offer spinal cord injury patients,” stated Jason Laufer, Chief Executive Officer, RDD Pharma.  ‘We have the potential to positively impact the health, well-being and quality of life in this patient population. ‘  Read more.

Source: PRNewswire, July 5, 2017

 

Christine Norton, PhD

2017 John J. Humpal Award Presented to Professor Christine Norton at Innovating for Continence Conference

The John J. Humpal award was presented to Professor Christine Norton at the Simon Foundation for Continence’s sixth biennial Innovating for Continence: The Engineering Challenge conference, hosted April 19-21 at the Millennium Knickerbocker Hotel, in Chicago, IL, USA.

Christopher Payne, MD, Emeritus Professor of Urology at Stanford University presented the John J. Humpal award to Christine Norton, PhD, MA, RN. Dr. Payne asked the conference attendees, “What makes a young, talented nurse scientist choose the field of fecal incontinence? While I don’t have the exact answer to that question, we are certainly lucky that she did. I first met Christine at the WHO International Consultation on Incontinence in 2005 and was struck by the clarity and insightfulness of her committee’s findings. Christine achieved the classic goal for medical faculty with major contributions in teaching, education, and clinical care. In fact, there is practically nothing in the entire field to which she has not contributed. For this she was awarded an endowed professorship. I’m a bit jealous, but very proud to be her colleague, and to present her this well-deserved award.”

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clostridium difficile

ConvaTec Releases New Fecal Management System in US

Global medical technology company ConvaTecGroup announced the US launch of the Flexi-Seal PROTECT Fecal Management System on Tuesday, following receipt of 510(k) clearance from the US Food and Drug Administration.  The FTSE 100 firm said Flexi-Seal PROTECT FMS was the latest addition to the company’s “market-leading range” of advanced systems developed to manage acute fecal incontinence, and help to reduce the associated risks of skin breakdown and spread of C. difficile infection.  Read more.

Source: digitallook.com, May 2, 2017

surgeons perform pelvic organ prolapse surgery

How a Ring of Titanium Beads Can Help Fecal Incontinence

A new device made up of magnetic titanium beads may help certain patients who have problems controlling their bowels, a condition called fecal incontinence.  The Fenix® Continence Restoration System mimics the function of the anal sphincter. It is the newest treatment option available to certain patients who have fecal incontinence caused by childbirth complications, trauma, prior surgeries, anal sex or another cause of muscle and nerve damage.  Read more.

Source: Cleveland Clinic, March 9, 2017

Health Canada logo

Axonics Sacral Neuromodulation System Receives Marketing Approval

Axonics Modulation Technologies, Inc. announced today that it received a Homologation d’un instrument médical (medical device approval) for the first rechargeable Sacral Neuromodulation (r-SNM™) System® to treat Overactive Bladder (OAB), Fecal Incontinence and Urinary Retention.  The Health Canada license confirms that the Axonics® product meets all of the Canadian Medical Devices Regulations, Section 36, for Active Implantable Medical Devices and enables Axonics to market its r-SNM System throughout Canada. Read more.

Source: Yahoo! Finance, January 5, 2017

The Simon Foundation for Continence Announces Its Innovating for Continence Conference 2017

Diane K. Newman

Diane K. Newman, DNP, ANP-BC, FAA, Honorary Conference President

This biennial, international conference series features a unique mix of engaging speakers that promise to provide fresh thinking on the topic of incontinence, including experts in areas of technology that have yet to be applied to continence care product development. The 2017 Honorary President for the conference is Dr. Diane K. Newman.
female athlete running thriathletes

Female Triathletes at Higher Risk for Pelvic Floor Disorders

Female triathletes are at a higher risk for several health issues, including pelvic floor disorders, new research indicates. Researchers conducted an internet survey of 311 self-identified female triathletes. Results showed a significant prevalence of pelvic floor disorders, with urinary incontinences (37.4 percent) and anal incontinence (28.0 percent) being the most common.  Read more.

Source: Science Daily, August 23, 2016

Living with VACTERL Association

My Story – Submitted by: Gerald

I was born in 1957 with VACTERL Association. I have a Klippel-Feil in both my cervical spine and lumbar spine (L1-L4 congenitally fused), a syrinx in lower cervical spine, urinary tract fistulas, imperforate anus, and a horseshoe kidney. I have a history of distension, pseudo-obstruction (for which I have been hopitalized and NG’d several times), two obstructions due to adhesions, and these were surgically repaired. I also have a syrinx in my lower cervical spine which is stable. I was also born with an imperforate anus and required a pull-thru at birth. I had laminectomies in both my cervical and lumbar spines (L1-L4 is congenitally fused with hemi-vertibrae, scolioses, severe stenosis in the foramen and central canal). I have a horseshoe kidney but do not have any renal issues that I am aware of, though I am prone to UTI’s. I am largely incontinent and have severe motility problems and am sometimes unable to pass stool for a week at a time. Continue reading

Learning to Live with Bladder and Bowel Incontinence

My Story – Submitted by: Shawn

Hello all! My name is Shawn and I am 39 years old and I am bowel and bladder incontinent. This started for me about 2 years ago. Well, l started out driving dump trucks for months and theses guys were dropping 2-3 thousand pound rocks into my truck. Jarred the snot out of me and knocked the wind right out of me several times. I started having issues with balance, feeling lightheaded all the time, blood pressure issues, couldn’t think or reason. And then one day I was sitting in bed talking to my wife, and wammo! I was wet. Soaked! Started having issues during the day peeing my pants and started wetting at night.Continue reading